Europeans have long been able to buy nonsteroidal anti-inflammatory drugs, or Nsaids (pronounced EN-seds), in creams and sprays to ease muscle and joint pain. In the U.S, the first topical Nsaid was approved 3 years ago. A new analysis of studies on the use of topical Nsaids for acute injuries like
sprains and strains show that topical Nsaids are as effective as pills in treating
osteoarthritis in the knee and hand as well as musculoskeletal injuries like soreness and
tendinitis. The advantage of Nsaid skin cream is that it bypasses the stomach and much of the bloodstream, minimizing side effects.
Nsaid cream and Nsaid spray deliver very high joint concentrations of the topical Nsaid, higher than with standard oral doses, with very low, and therefore very safe, blood levels. Patients taking Nsaid pills have a much higher rate of
indigestion,
diarrhea,
abdominal pain, abnormal liver tests and
anemia than those using the cream.
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